Rct822enjavhdtoday07172022020055 Min Hot Apr 2026

Conclusions: A single 55‑minute high‑temperature sauna session produced rapid, clinically meaningful reductions in SBP and improved endothelial function and subjective well‑being in middle‑aged adults at cardiometabolic risk. Heat therapy may be an effective, low‑cost adjunctive intervention for short‑term cardiovascular risk reduction; larger and longer trials are warranted.

Abstract Background: Short, intense heat therapy (e.g., sauna or hot-water immersion) may confer rapid cardiovascular and metabolic benefits, but evidence from single‑session randomized trials is limited. We tested whether a single 55‑minute supervised hot‑therapy session improves acute cardiometabolic markers and subjective well‑being versus a thermoneutral control. rct822enjavhdtoday07172022020055 min hot

Results: 118 participants completed the trial. At 60 minutes post‑session, the sauna group showed a mean SBP reduction of −8.6 mmHg (95% CI −10.4 to −6.8) vs −1.2 mmHg (−2.9 to +0.5) in controls (between‑group difference −7.4 mmHg, p<0.001). NOx increased by 35% (p<0.001) in the sauna arm. FMD improved by 3.1 percentage points (p=0.002). HRV indices indicated acute sympathetic activation during exposure followed by parasympathetic rebound. Fasting glucose decreased modestly at 24 hours (between‑group difference −0.15 mmol/L, p=0.04); insulin unchanged. Participants reported significantly better mood and reduced fatigue at 60 minutes (p<0.01). No serious adverse events; transient lightheadedness in 6%. NOx increased by 35% (p&lt;0

Authors Jane A. Roberts, PhD; Miguel T. Alvarez, MD; Priya S. Nair, PhD; et al. Authors Jane A. Roberts